Scientific Name: Mus musculus
Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Euarchontoglires-> Glires-> Rodentia-> Myomorpha-> Muroidea-> Muridae-> Murinae-> Mus-> Mus
Summary: This gene encodes a glycan-binding receptor and member of the C-type lectin family which plays a role in the immune response. C-type lectin receptors are pattern recognition receptors located on immune cells that play a role in the recognition and uptake of both self and non-self glycoproteins as well as mediating cell adhesion, glycoprotein clearance, and cell signaling functions. This gene's protein binds complex-type N-glycans of the viral envelope proteins of Ebola virus, West Nile filovirus, and SARS coronavirus, but not HIV or hepatitis C virus. In mouse, this protein has been shown to recognize activated T-cells and to negatively regulate T-cell receptor-mediated signalling. It also acts as a novel, liver-specific regulator of NK cell-mediated immunity in mouse. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2022] [NCBI] [Proteinatlas]
Data set information
Project | Date | Technology | Tissue | Condition | Cell | PMID/DOI |
---|---|---|---|---|---|---|
Vthunter_110001 | 2018.02 | Microwell-seq | Bladder | Normal | 2746 | Link |
Vthunter_110002 | 2018.02 | Microwell-seq | BoneMarrow | Normal | 510 | Link |
Vthunter_110004 | 2018.02 | Microwell-seq | BoneMarrowcKit | Normal | 13019 | Link |
Vthunter_110006 | 2018.02 | Microwell-seq | Brain | Normal | 3285 | Link |
Vthunter_110007 | 2018.02 | Microwell-seq | Brain | Normal | 753 | Link |
Vthunter_110011 | 2018.02 | Microwell-seq | Fetal Intestine | Normal | 6076 | Link |
Vthunter_110012 | 2018.02 | Microwell-seq | Fetal Lung | Normal | 6453 | Link |
Vthunter_110014 | 2018.02 | Microwell-seq | Fetal Stomach | Normal | 6192 | Link |
Vthunter_110015 | 2018.02 | Microwell-seq | Kidney | Normal | 4682 | Link |
Vthunter_110016 | 2018.02 | Microwell-seq | Liver | Normal | 4424 | Link |
Vthunter_110017 | 2018.02 | Microwell-seq | Liver | Normal | 261 | Link |
Vthunter_110018 | 2018.02 | Microwell-seq | Lung | Normal | 2512 | Link |
Vthunter_110019 | 2018.02 | Microwell-seq | Lung | Normal | 1414 | Link |
Vthunter_110020 | 2018.02 | Microwell-seq | Lung | Normal | 3014 | Link |
Vthunter_110021 | 2018.02 | Microwell-seq | MammaryGland.Involution | Normal | 3510 | Link |
Vthunter_110022 | 2018.02 | Microwell-seq | MammaryGland.Involution | Normal | 1311 | Link |
Vthunter_110024 | 2018.02 | Microwell-seq | MammaryGland.Lactation | Normal | 6905 | Link |
Vthunter_110025 | 2018.02 | Microwell-seq | MammaryGland.Pregnancy | Normal | 4909 | Link |
Vthunter_110027 | 2018.02 | Microwell-seq | MammaryGland.Virgin | Normal | 1059 | Link |
Vthunter_110028 | 2018.02 | Microwell-seq | MammaryGland.Virgin | Normal | 648 | Link |
Vthunter_110030 | 2018.02 | Microwell-seq | MesenchymalStemCells | Normal | 7365 | Link |
Vthunter_110031 | 2018.02 | Microwell-seq | MesenchymalStemCellsPrimary | Normal | 7319 | Link |
Vthunter_110033 | 2018.02 | Microwell-seq | Muscle | Normal | 1102 | Link |
Vthunter_110034 | 2018.02 | Microwell-seq | NeonatalCalvaria | Normal | 4347 | Link |
Vthunter_110035 | 2018.02 | Microwell-seq | NeonatalCalvaria | Normal | 3617 | Link |
Vthunter_110036 | 2018.02 | Microwell-seq | NeonatalHeart | Normal | 3948 | Link |
Vthunter_110037 | 2018.02 | Microwell-seq | NeonatalMuscle | Normal | 829 | Link |
Vthunter_110038 | 2018.02 | Microwell-seq | NeonatalMuscle | Normal | 4044 | Link |
Vthunter_110039 | 2018.02 | Microwell-seq | NeonatalPancreas | Normal | 4571 | Link |
Vthunter_110040 | 2018.02 | Microwell-seq | NeonatalRib | Normal | 1217 | Link |
Vthunter_110041 | 2018.02 | Microwell-seq | NeonatalRib | Normal | 3082 | Link |
Vthunter_110042 | 2018.02 | Microwell-seq | NeonatalRib | Normal | 1963 | Link |
Vthunter_110043 | 2018.02 | Microwell-seq | NeonatalSkin | Normal | 3392 | Link |
Vthunter_110045 | 2018.02 | Microwell-seq | Pancreas | Normal | 3610 | Link |
Vthunter_110047 | 2018.02 | Microwell-seq | PlacentaE14.1 | Normal | 1873 | Link |
Vthunter_110048 | 2018.02 | Microwell-seq | PlacentaE14.2 | Normal | 2473 | Link |
Vthunter_110051 | 2018.02 | Microwell-seq | SmallIntestine | Normal | 3438 | Link |
Vthunter_110052 | 2018.02 | Microwell-seq | SmallIntestine | Normal | 1671 | Link |
Vthunter_110053 | 2018.02 | Microwell-seq | SmallIntestine | Normal | 1575 | Link |
Vthunter_110054 | 2018.02 | Microwell-seq | Spleen | Normal | 1970 | Link |
Vthunter_110055 | 2018.02 | Microwell-seq | Stomach | Normal | 2389 | Link |
Vthunter_110056 | 2018.02 | Microwell-seq | Testis | Normal | 2216 | Link |
Vthunter_110057 | 2018.02 | Microwell-seq | Testis | Normal | 11789 | Link |
Vthunter_110060 | 2018.02 | Microwell-seq | Uterus | Normal | 1704 | Link |
Vthunter_110066 | 2019.12 | MARS-seq | TotalBrain | Normal | 2304 | Link |
Vthunter_110101 | 2020.09 | 10X Genomics | Teeth | Teeth | 2888 | Link |
Vthunter_110105 | 2018.07 | 10X Genomics | Adipose | Adipose | 288 | Link |
Vthunter_110106 | 2016.02 | 10X Genomics | PrimaryVisualCortex | PrimaryVisualCortex | 1787 | Link |
Featureplot of receptors
Expression: Biased expression in liver (RPKM 17.2), lymph node (RPKM 6.5) and 6 other tissues